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  2. Although appropriate studies on the relationship of age to the effects of modafinil have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of modafinil in the elderly. Off-label use means the drug has been approved for one use, but is used for another. The higher no-effect dose for rat embryofetal developmental provigil side effects toxicity was associated with a plasma modafinil exposure approximately.5 times the AUC in humans at the recommended daily dose (RHD) of 200.

  3. The enantiomers of modafinil exhibit linear kinetics upon multiple dosing of 200-600 mg/day once daily in healthy volunteers. Note that this list of side provigil generic effects does not replace the complete one that comes in your provigil generic Provigil package insert. Sleep Quiz: Test Your Medical.